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Rino Rappuoli Fondazione Biotecnopolo di Siena, Italy Florence is the city of the Renaissance, the historical period between AD 1450 and 1600 that marked the cultural transition from the Middle Ages to the modern era. During this period Filippo Brunelleschi used revolutionary innovation to build the Dome of the Florentine Cathedral, and other giant artists like Piero della Francesca, Leonardo da Vinci, Mi...
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